Academic Thesis
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Basic information
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| Name | Mitsumoto Atsushi |
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Effects of phenobarbital and dosing time on the plasma concentration and pharmacological activity of tadalafil in mice. |
Joint Author
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Hiroshi Kawai, Naoki Takeda, Naoko Kojima, Reiko Iwadate, Naomi Kudo, Atsushi Mitsumoto.
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In mice, the plasma tadalafil concentration tended to be higher when administered in the morning than in the evening. In contrast, plasma tadalafil concentration was higher when administered in the evening than in the morning in mice pretreated with phenobarbital. The coadministration of phenobarbital and tadalafil may suppress the plasma levels and pharmacological activities of tadalafil.
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BPB Reports |
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8
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3
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86
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91
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2025/06
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Exist
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Not exist
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English
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Research papers (academic journals)
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International
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Not International Collabolation
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https://doi.org/10.1248/bpbreports.8.3_86
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Url
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Not Downloadable
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Main Achievement