Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates
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Aranapakam M Venkatesan, Yansong Gu, Osvaldo Dos Santos, Takao Abe, Atul Agarwal, Youjun Yang, Peter J Petersen, William J Weiss, Tarek S Mansour, Michiyoshi Nukaga, Andrea M Hujer, Robert A Bonomo, James R Knox