Academic Thesis

Basic information

Name Tashima Kimihito
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Title

Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats

Bibliography Type

Joint Author

Author

Tashima K, Fujita A, Umeda M, and Takeuchi K.

OwnerRoles

Summary

 We conclude that NCX-4016 does not have a toxic effect in either normal or diabetic rat stomachs, although the diabetic rat stomach is more vulnerable to ASA-induced damage. NCX-4016, though absorbed more slowly than ASA, counteracts the injurious effect of aspirin on the gastric mucosa, probably by increasing GMBF mediated by NO.

Magazine(name)

Life Sci.

Publisher

Volume

67

Number Of Pages

13

StartingPage

1639

EndingPage

1652

Date of Issue

2000/08

Referee

Exist

Invited

Not exist

Language

English

Thesis Type

Research papers (academic journals)

International Journal

International

International Collaboration

International Collabolation

ISSN

eISSN

DOI

10.1016/s0024-3205(00)00746-3.

NAID

Cinii Books Id

PMID

10983857

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URL

Format

Url

Download

Not Downloadable

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arXiv ID

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DBLP ID

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Other