Formal total synthesis of macrosphelide (+)-A, effect on macrolactonization depended upon the lactone formation position
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Summary
Formal total synthesis of (+)-macrosphelide A (I) was achieved based on macrolactonization via path B from a seco-acid (II) and path C from a seco-acid (III). The yield of macrolactonization via paths B and C were 18 and 59%, resp. (2002), 57(2), 327-336