The intramolecular Pauson-Khand reaction of various 2-aryl-1-hepten-
6-ynes and its aza-derivatives (exo-olefins) efficiently produced arylbicyclo[
3.3.0]octenones and azaoctenone bearing quaternary carbon centers at
angular positions in good yields. Although a similar reaction of 2-phenyl-1-octen-
7-yne (exo-olefin), which is a homologue of 2-phenyl-1-hepten-6-yne, did not take place, the reaction of the methyl derivatives smoothly proceeded. However, the reaction of regioisomeric 1-phenyl-1-octen-7-yne (endo-olefin) afforded the desired product in moderate yields.
pp.1359-1374
