Exogenous insulin-like growth factor (IGF)-1 improves the impaired healing of gastric mucosal lesions in diabetic rats

Korolkiewicz RP, Tashima K, Fujita A, Kato S, Takeuchi K.

These results suggest that DM has a deleterious influence on the healing of acute gastric lesions in both insulin- and IGF-1-sensitive manner. The systemic administration of rhIGF enhanced the rate of healing of gastric lesions observed in the healing-impaired STZ-diabetic animals.

Pharmacol Res.

41

2

10.1006/phrs.1999.0581

10623490