Manifestation of psychiatric behaviors in a mouse model of griseofulvin-induced hepatic porphyria.

Satoh Y, Iwadate R, Watanabe Y, Kawai H, Kudo N, Kawashima Y, Mitsumoto A.

In porphyria mice produced by ingesting griseofulvin, it was shown that neuropsychiatric symptoms such as anxiety and depressive symptoms can be evaluated under the condition that abnormal heme metabolism and liver damage occur as chronic disorders.

J Toxicol Sci.

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