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基本情報
| 氏名 |
田嶋 公人 |
| 氏名（カナ） |
タシマ キミヒト |
| 氏名（英語） |
Tashima Kimihito |
| 所属 |
薬学部 医療薬学科 |
| 職名 |
教授 |
| researchmap研究者コード |
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| researchmap機関 |
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Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats
Tashima K, Fujita A, Umeda M, and Takeuchi K.
We conclude that NCX-4016 does not have a toxic effect in either normal or diabetic rat stomachs, although the diabetic rat stomach is more vulnerable to ASA-induced damage. NCX-4016, though absorbed more slowly than ASA, counteracts the injurious effect of aspirin on the gastric mucosa, probably by increasing GMBF mediated by NO.
10.1016/s0024-3205(00)00746-3.
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