Tissue distribution and hepatic subcellular distribution of perfluorooctanoic acid at low dose are different from those at high dose in rats.
Bibliography Type
Joint Author
Author
Kudo N, Sakai A, Mitsumoto A, Hibino Y, Tsuda T, Kawashima Y.
OwnerRoles
Summary
Dose-based differences in tissue distribution and hepatocyte distribution in perfluorooctanoic acid-fed rats were investigated. It was found to be distributed in the rat liver, particularly in the membrane fraction, and excreted in the bile, especially at low dose exposures.