Changes of Energy Metabolism Induced by 1-Methyl-4-phenylpyridinium (MPP+)-related Compounds in Rat Pheochtomocytoma PC12 Cells
単著・共著の別
共著
著者
D. Kang, K. Miyako, F. Kuribayashi, E. Hasegawa, A. Mitsumoto, T. Nagano, and K. Takeshige
担当区分
概要
We synthesized various 1-methyl-4-phenylpyridinium (MPP+) derivatives and examined their energy metabolism levels in cultured neurons. From this study, we clarified that the parkinsonism-related substances have not only mitochondrial inhibitory activity but also an effect to change energy metabolism.