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基本情報
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| 氏名 | 光本 篤史 |
| 氏名(カナ) | ミツモト アツシ |
| 氏名(英語) | Mitsumoto Atsushi |
| 所属 | 薬学部 医療薬学科 |
| 職名 | 教授 |
| researchmap研究者コード | |
| researchmap機関 |
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A Dual Effect of 1-Methyl-4-phenylpyridinium (MPP+)-analogs on the Respiratory Chain of Bovine Heart Mitochondria.
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We synthesized various 1-methyl-4-phenylpyridinium (MPP+) derivatives and examined their structural relationships in respiratory chain inhibitory activity using isolated mitochondria. From this study, it was clarified that MPP+ analogues have both electron transfer inhibitory effect and active oxygen production enhancing effect.