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Basic information
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Koyanagi Junichi |
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Researcher Basic Information
Work Situation After Establishment of College |
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Researcher Activity Information
- Nitration of 2-Carbonyl-3,4-Dichlorofuran Derivatives 共著 Org. Prep. Proced. Int., 21, 249-251 (1989) 1989/04
- Preparation of 3-Bromo-2-methylfuran and 4-Bromo-2-methylfuran 共著 J. Heterocycl. Chem., 31, 1093-1905 (1994) 1994/07
- A Short-step Synthesis of Naphtho[2,3-b]furan-4,9-dione 共著 J. Heterocycl. Chem., 31, 1303-1304 (1994) 1994/09
- A Facile Synthesis of 2-Acetylnaphtho[2,3-b]furan-4.9-dione 共著 J. Heterocycl. Chem., 32, 1289-1291 (1995) 1995/07
- Synthesis of New Tricyclic Compound, 5H-2-Methoxycarbonyl-4-oxofuro[2,3-b][1,5]benzothiazepine 共著 Chem. Pharm. Bull., 43, 2064-2067 (1995) 1995/12
- A Short Synthesis of 4-(3-Furyl)-4-oxobutanoic Acid and Synthesis of Egomaketone 共著 J. Nat. Prod., 58, 1955-1957 (1995) 1995/12
- A New Synthetic Route to 2-Substituted Naphtho[2,3-b]furan-4,9-dione 共著 J. Heterocycl. Chem., 34, 407-412 (1997) 1997/03
- Nucleophilic Substitutions of 2-Halonaphtho[2,3-b]furan-4,9-diones and 2-Nitronaphtho[2,3-b]furan-4,9-dione 共著 Chem. Pharm. Bull., 45, 1579-1581 (1997) 1997/10
- Nucleophiloc Substitutions of 2-Chloronaphtho[2,3-b]furan-4,9-dione with amines 共著 J. Heterocycl. Chem., 35, 301-305 (1998) 1998/03
- 「Facile Synthesis of Furobenzothiazepines 共著 J. Heterocycl. Chem., 36, 819-822 (1999) 1999/05
- Site-Selective Trifluoroacetylation of Dimethylamino-Substituted Pyridines and Its Use as a Building Block for Trifluoromethyl-Containing Heterocycles 共著 Chem. Pharm. Bull., 47, 718-719 (1999) 1999/05
- Spirostanols Obtained by Cyclization of Pseudosaponin Derivatives and Comparison of Anti-Platelet Agglutination Activities of Spirostanol Glycosides 共著 Eur. J. Med. Chem., 35, 511-527 (2000) 2000/05
- Cyanoglycosylation Accompanied by Ring-Opening of Spirostanols 共著 Heterocycles, 53, 1745-1764 (2000) 2000/08
- Bromination of Steroidal Hormone Having α,β-Unsaturated Ketone, 17-O-acetyltestrosterone, in the Presence of Silver Triflate 共著 Chem. Pharm. Bull., 49, 23-28 (2001) 2001/01
- Spongistatin Synthetic Studies. An Efficient Second-Generation Construction of Advanced ABCD Intermediate 共著 Organic Letters, 4, 783-786 (2002) 2002/03
- Preparation of Heterospirostanols and Their Pharmacological Activities 共著 Eur. J. Med. Chem., 37, 659-669 (2002) 2002/08
- 4’-O-Alkylaloenin derivatives and their sulfates directed toward overcoming multidrug resistance in tumor cell 共著 Cancer Letters, 218, 15-30 (2005). 2005/01
- Preparations of vitamin D analogs, spirostanols and furostanols, from diosgenin and their cy totoxic activities 共著 Eur. J. Med. Chem., 40, 662-673 (2005). 2005/07
- Reactionｓ of 26-Iodopseudodiosgenin and 26-Iodopseudodiosgenon with Various Nucleophiles and Pharmacological Activities of the Products 共著 Chem. Pharm. Bull., 54（1）, 72－79 (2006) 2006/01
- Cytotoxic Activity toward KB Cells of 2-Substituted Naphtho[2,3-b]furan-4,9-diones and Their Related Compounds 共著 Biosci. Biotechnol. Biochem., 70(4), 1009-1012 (2006) 2006/04
- Synthesis of Phenyl Furyl Sulfides and Phenyl Furyl Ethers by Nucleophilic Substitution of Nitrofurans 共著 J. Heterocyclic Chem., 44(5), 1145-1148 (2007) 2007/10
- Preparation of 1,8-di-O-alkylaloe-emodines and 15-amino, 15-thiocyano, and 15-selenocyanochrysophanol derivatives from aloe-emodine and studying their cytotoxic effects 共著 Chem. Pharm. Bull. 56(4) 487-503 (2008) 2008/04
- Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones 共著 Eur. J. Med. Chem., 43(6), 1206-1215 (2008) 2008/06
- Tumor-specific cytotoxicity and type of cell death induced by naphtho[2,3-b]furan-4,9-diones and related compounds in human tumor cell lines: relationship to electronic structure. 共著 Anticancer Research (2009), 29(1), 455-464. 2009/01
- Spongistatin synthesis studies. Evolution of a scale totao synthesis of (+)-spongistatin 1 共著 Tetrahedron (2009), 65(33), 6489-6509 2009/08
- 薬学教育モデル・コアカリキュラムに準拠した六年制薬学教育における学生の達成感に関する自己評価の一例 共著 薬学雑誌133(1) 141-148 (2013) 2013/01
- FICA, a new chiral derivatizing agent for determining the absolute configuration of secondary alcohols by 19F and 1H NMR 共著 Tetrahedron: Asymmetry 24(17)1001-1009(2013) 2013/09
- Reductive metabolism of nabumetone by human liver microsomal and cytosolic fractions: exploratory prediction using inhibitors and substrates as marker probes 共著 European Journal of Drug Metabolism and Pharmacokinetics, 2014/03
- Improved Synthetic Route to Methyl 1-Fluoroinda-1-carboxylate (FICA Me Ester) and 4-Methyl Derivatives 共著 Chem. Pharm. Bull.,62, 816-819 2014) 2014/08
- Determination of the Absolute Configuration of the Nabumetone Metabolite 4-(6-Methoxy-2-naphthyl)butan-2-ol Using the Chiral Derivatizing Agent, 1-Fluoroindan-1-carboxylic acid 共著 Chem. Pharm. Bull.,67, 75-78 (2019). 2019/01
- A metabolic pathway for the prodrug nabumetone to the pharmacologically active metabolite, 6-methoxy-2-naphthylacetic acid (6-MNA) by non-cytochrome P450 enzymes 共著 Xenobiotica, 50, 783-792 (2020) 2020/04
- Synthesis and Evaluation of FICA Derivatives as Chiral Derivatizing Agents 共著 Chem. Pharm. Bull., 68, 818-821 (2020) 2020/07
- Role of human flavin-containing monooxygenase (FMO) 5 in the metabolism of nabumetone: Baeyer-Villiger oxidation in the activation of the intermediate metabolite, 3-hydroxy nabumetone, to the active metabolite, 6-methoxy-2-naphthylacetic acid in vitro 共著 Xenobiotica, 51, 155-166 (2021) 2021/01
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